Educational

Settembre 9, 2023

Different faces of ovarian granulosa cell tumors: spectrum of MR imaging findings

1. Nucci MR. (2019). Sex-cord stromal tumors of the ovary. In Parra-Herran C (ed.), Gynecologic pathology (2nd ed., pp 643-706). Elsevier. 2. Causa-Andrieu P, Nicola R, Lipsich F, Adri D, Gomez M, Pol M, Wernicke A, Saraniti G, Chacon CR. Characterization of Ovarian Granulosa Cell Tumors using Magnetic Resonance Imaging. Med Res Arch;10(6):10.18103/mra.v10i6.2813. 3. Zhang J, Zhang Y, Guo Y. Combination of clinical and MRI features in diagnosing ovarian granulosa cell tumor: A comparison with other ovarian sex cord-gonadal stromal tumors. Eur J Radiol 2023;158:110593. 4. Rha SE, Oh SN, Jung SE, Lee YJ, Lee AW, Byun JY. Recurrent ovarian granulosa cell tumors: clinical and imaging features. Abdom Imaging 2008;33(1):119-25. 5. Tanaka YO, Saida TS, Minami R, Yagi T, Tsunoda H, Yoshikawa H, Minami M. MR findings of ovarian tumors with hormonal activity, with emphasis on tumors other than sex cord-stromal tumors. Eur J Radiol 2007;62(3):317-27. 6. Zhang H, Zhang H, Gu S, Zhang Y, Liu X, Zhang G. MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors. J Ovarian Res 2018;11(1):46.
Settembre 7, 2023

Differentiation between an enlarged cyst and a hydronephrosis mimicking a large cyst: a critical checking point for guiding a treatment plan in PCKD patients with symptomatic or complicated cyst

polycystic kidney disease, duplication, hydronephrosis, ethanol sclerotherapy
Settembre 9, 2023

Differentiation of endometriomas from ovarian hemorrhagic cysts on magnetic resonance imaging – a pictorial review

Teaching Objectives Endometriomas and ovarian hemorrhagic cysts are common ovarian masses that may appear similar on MRI. Differentiating between them is important for clinical management. The purpose of this poster is to outline the key imaging features that can help distinguish between these two entities on MRI. This exhibit intends to be a helpful tool for radiology residents and radiologists. Review of the topic Hemorrhagic cysts usually result from hemorrhage into a corpus luteum or other functional cysts, whereas endometriomas result from endometrial tissue that grows into ovaries. Endometriomas typically appear as well-defined cystic lesions with homogeneous high signal on T1 and low signal on T2-weighted images owing to the presence of deoxyhemoglobin and methemoglobin (shading sign), which is very suggestive of an endometrioma. Finding a “T2 dark spot” sign is specific for chronic hemorrhage and is useful in diagnosing endometriomas. Endometriomas may have wall enhancement on post-contrast images. The presence of an enhancing mural nodule is suggestive of malignant transformation. Ovarian hemorrhagic cysts may have variable signal intensity on both T1 and T2-weighted images due to the presence of blood products at various stages of degradation. They are usually hyperintense on T1 and T2- weighted images and do not show loss of signal on T1 fat-suppressed sequences, which is important for differentiating it from a mature cystic teratoma of the ovary. Hemorrhagic cysts may have a thickened cyst and do not enhance on post-contrast images. Conclusion Differentiating endometriomas from ovarian hemorrhagic cysts on MRI can be challenging, but careful assessment of the lesion's features on MRI can help differentiate these entities. Proper identification of these lesions is important for appropriate clinical management.
Settembre 9, 2023

Diffusion-weighted imaging of the urinary tract – beyond tumors

Acute and Chronic Kidney Disease (CKD) are still important causes of morbi-mortality. Due to important limitations of laboratorial markers like microalbuminuria and serum creatinine, other techniques have been studied over the last decades. We provide a pictorial review with MR images from our institution, depicting the Diffusion-weighted imaging (DWI) features of acute kidney disease (including Acute Pyelonephritis (APN), hydronephrosis, abscesses, hematomas and sediment) and CKD. DWI assesses restriction to water molecules diffusion, as well as blood microcirculation and tubular flow, being a promising biomarker of the renal microstructure. Changes on renal perfusion, glomerular and tubular flow can thus modify both renal DWI signal and Apparent Diffusion Coefficient (ADC). APN, CKD, and obstruction typically exhibit restriction to water diffusion, with corresponding low cortical ADC values. Hematomas, abscesses and sediment also exhibit restriction and tend to appear particularly bright at high b values. In the set of acute infection, the lack of ionizing radiation makes DWI very attractive during pregnancy and childhood. Also, Diffusion Tensor Imaging (DTI), by measuring fractional anisotropy, provides an even better characterization of the renal microstructure, particularly in CKD, being able to depict alterations earlier than conventional blood biomarkers. After adequate standardization of these sequences, still under investigation, the need for biopsy and contrast administration can be obviated, highlighting DWI not only as a diagnostic tool but also as way to follow-up and guide treatment decisions. The importance of DWI goes well beyond tumor detection, particularly in the kidney. It is an increasingly recognized biomarker of renal function and fibrosis, namely in CKD. The role of DWI in APN and obstruction has also been explored and its imaging findings should figure in the checklist of the urogenital radiologist.
Settembre 9, 2023

Gastric-Type Adenocarcinoma of the Uterine Cervix: Role of Magnetic Resonance Imaging for Diagnosis and Management

Gastric-type adenocarcinoma of the uterine cervix is an aggressive, human papillomavirus-independent subtype carrying poor prognosis, with greater propensity for metastases, and resistance to chemotherapy and radiotherapy. Distinctive MRI features of intratumoral cysts, upper endocervical location with endophytic growth, and heterogeneous enhancement which can aid in identification of GAS and differentiation from cervical squamous cell carcinoma and other benign cervical multicystic lesions. Targeted and adequate biopsy on suspicious solid areas identified on MRI is crucial for early definitive histological diagnosis. High soft-tissue resolution of MRI and the use of dedicated double-oblique imaging planes allows accurate local tumour staging. Diffusion-weighted imaging and enhancement pattern make MRI indispensable in differentiating between post-irradiation fibrosis and recurrent tumour on post-treatment follow-up.
Settembre 9, 2023

Genitourinary fluoroscopic contrast examinations: what role do they have today?

1. Working group SIRM-SIAARTI-SNR-AINR coordinator Tamburrini O. I mezzi di contrasto in diagnostica per immagini, raccomandazioni all’uso, reazioni avverse e trattamento, Omicron Editrice Genova. 2. R Ruiz-Cruces 1, F Ruiz, M Pérez-Martínez, J López, I Tort Ausina, A D de los Ríos; Patient dose from barium procedures, Br J Radiol . 2000 Jul;73(871):752-61. doi: 10.1259/bjr.73.871.11089468. 3. Disantis DJ, Lewis JI, Menias CO, Balfe DM, Morgan DE, Cernigliaro JG. Imaging tips for performing a perfect barium swallow. Radiographics. 2019 Sep-Oct;39(5):1325-6. 4. A. L. F. Yasin, O. Aljaziri, A. H. M. Sha'ban, A. Yousaf, F. S. R. Ameerudeen Moulana, M. A. H. Shah; A radiologist’s guide to the role of urethrography in the assessment of urethral diseases in adult males, DOI 10.26044/ecr2021/C-10954 https://epos.myesr.org/poster/esr/ecr2021/C-10954/findingsandproceduredetails 5. Catalá V et al: CT findings in urinary diversion after radical cystectomy: postsurgical anatomy and complications. Radiographics. 29(2):461-76, 2009 6. Hysterosalpingography: a reemerging study. Simpson WL Jr, Beitia LG, Mester J. Radiographics. 2006 Mar-Apr;26(2):419-31. 7. Chalazonitis, A., Tzovara, I., Laspas, F., Porfyridis, P., Ptohis, N., & Tsimitselis, G. (2009). Hysterosalpingography: technique and applications. Current Problems in Diagnostic Radiology, 38(5), 199–205. https://doi.org/10.1067/j.cpradiol.2008.02.003
Settembre 9, 2023

Gynecological Masses: Tips for Determining their Site of Origin

The identification of the origin and nature of gynecological pelvic masses can be challenging. The most common origin of lesions of the upper female reproductive tract lesions is the ovaries. Radiological clues to identify an ovarian origin are the Phantom Ovary Sign, the Ovarian Vascular Pedicle Sign, the Beak Sign, the Ovarian Crescent Sign, and the Posterior Displacement of extraperitoneal structures. In cases where an ovarian origin is ruled out, attention is directed to consider a fallopian tube origin. The characteristic morphological signs are the Cogwheel Sign, the Waist Sign, and the "C" or "S" shaped configuration. Furthermore, the possibility of a uterine origin can be suspected by the Claw Sign and the Bridging Vessel Sign. There are also pelvic gynecological masses with origin in the broad ligament, vagina, and cervix. Concluding, radiological features, along with clinical information, aid in narrowing the differential diagnosis.
Settembre 9, 2023

Gynecological surgery’s complication: a radiological anatomical based approach to the diagnosis

Gynecological surgery is not free from complications and their correct diagnosis is essential for patient management.Compartmentalization of the pelvic anatomy can assist the radiologist in identifying the correct post surgical complications.
Settembre 9, 2023

High intensity focused ultrasound (HIFU) in the treatment of cancer of the prostate – Our experience

BIBLIOGRAPHY 1. Salgaonkar VA, Prakash P, Rieke V, et al. Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array.Med Phys. 2014;41(3):033301. doi:10.1118/1.4866226) 2. ChaussyCG: Ultrasonidos de alta intensidad focalizados(HIFU) para el tratamiento local del cancerde prostata: papel actual. Archivos Españoles de Urología, 2011; 64: 493–96 NCCN Guidelines® -Prostate Cancer Version 4.2022 3. ChaussyC, ThueroffS: Complete remission in metastatic prostate cancer after combined local and systemic therapy. Urology, 2006; 68: 197–98 4. Vyacheslav S, Leonid S, Mikhail V, Ravil K: High-Intensity Focused Ultrasound (HIFU) For the Prostate Cancer: 5-year Experience. International Journal of Tumor Therapy, 2012; 1: 20–25 5. Muller BG, FüttererJJ, Gupta RT, et al. The role of magnetic resonance imaging (MRI) in focal therapy for prostate cancer: recommendations from a consensus panel.BJU Int. 2014;113(2):218-227. doi:10.1111/bju.12243 6. Poissonnier L, Chapelon JY, Rouviere O et al: Control of prostate cancer by transrectal HIFU in 227 patients. Eur Urol, 2007;51: 381–87 7. BlanaA, Walter B, RogenhoferS et al: High-intensity focused ultrasound for the treatment of localized prostate cancer: 5-year experience. Urology, 2004; 63: 297–300 8. Uchida T, OhkusaH, Yamashita H et al: Five years experience of transrectal high-intensity focused ultrasound using the sonablatedevice in the treatment of localized prostate cancer. Int J Urol, 2006; 13: 228–33